Codsiyada Badeecada

1) Broilers

Marka MMHAC-yada (CHELATE-yada hydroxy methionine ee naxaasta, zinc, iyo manganese) ayaa lagu daray cuntooyinka digaagga lagu kariyo, natiijooyinku waxay muujiyeen in - marka la barbar dhigo macdanta raadadka aan dabiiciga ahayn ee dhaqameed - ku darista MMHAC-yada si weyn ayay u kordhisay miisaanka jidhka iyo miisaanka muruqa durbaanka (bowdada), waxay hagaajisay dheefshiidka naxaasta, mana aysan saameyn xun ku yeelan caafimaadka lafaha ama ciridka.

Shaxda 1. Miisaanka farsamaynta meydka (g/shimbir) iyo naaska qoryaha leh iyo naaska cad ee naaska oo tirooyin digaag ah oo la siiyay dawooyin aan dabiici ahayn iyo methionine hydroxyl oo ah daawada zinc, copper, iyo manganese oo analog ah maalintii 42aad.

Shay	ITM	M10	T125	M30	SEM	Qiimaha P
Naas	684	716	719	713	14.86	0.415
Bowdada	397	413	412	425	7.29	0.078
Durbaan garaac	320	335	332	340	4.68	0.058
Bowdada iyo durbaanka	717 a	748 ab	745 ab	765 b	11.32	0.050
Suufka dufanka leh	32.3	33.1	33.4	35.5	1.59	0.546
Beerka	68.0	67.4	66.0	71.1	2.41	0.528
Wadnaha	18.8	18.6	19.2	19.2	0.68	0.898
Kelyaha	9.49	10.2	10.6	10.6	0.51	0.413

Fiiro gaar ah: ITM: Macdanta raad-raaca aan noolayn 110 ppm Zn sida ZnSO4 16 ppm Cu sida CuSO4 iyo120 ppm Mn sida MnO sida Ross 308 talooyin nafaqo;

M10: Xaddiga 40 ppm Zn 10 ppm Cu iyo 40 ppm Mn sida chelate;

T125: Macdanta raad-raaca aan noolayn 110 ppm Zn sida ZnSO4 iyo 120 ppm Mn sida MnO sida tilmaamaha Ross 308 oo leh 125 ppm Cu sida koloriin naxaas ah oo saddex-geesood ah (TBCC);

M30 = 40 ppm Zn, 30 ppm Cu, iyo 40 ppm Mn sida chelate. Qiimaha isku midka ah ee leh qoraallo sare oo kala duwan ayaa si weyn u kala duwan (P < 0.05).

2) Doofaar

Daraasad ayaa baartay saameynta qayb ahaan ku beddelka macdanta aan dabiiciga ahayn methionine hydroxy analogue chelates (MMHAC) ee cuntooyinka abuurka ee abuurka iyo doofaarradooda labadaba. Natiijooyinku waxay muujiyeen in kaabista MMHAC ay yareysay miisaanka jidhka ee abuurka nuujinaya, ay kor u qaadday miisaanka jidhka doofaarka maalinta 18aad, ay si weyn u xoojisay heerarka acetylation ee muruqa lafaha histone markii la dhalayay, waxayna hoos u dhigtay muujinta hidde-sideyaal badan oo barar iyo horumarinta murqaha la xiriira. Guud ahaan, MMHAC waxay wanaajisay caafimaadka xiidmaha iyo horumarka murqaha ee doofaarrada iyada oo loo marayo nidaaminta epigenetic iyo koritaanka, taasoo kor u qaadaysa awooddooda korriin.

Shaxda 2 Saamaynta dheeraadka ah ee chelate-ka methionine hydroxy analogue ee cuntooyinka abuurka marka la eego muujinta mRNA-da muhiimka ah ee la xiriirta bararka jejunal ee doofaarka nuugaya.

Shay	ITM	CTM	SEM	P- qiimaha
d 1 ee nuujinta x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (p50)	701	693	93	0.944
NF-κB (p105)	1991	1646	211	0.274
TGF-b1	Laga bilaabo 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 naas nuujinta x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Fiiro gaar ah: Interleukin-8 (IL-8), mucin-2 (MUC2), nukliyeerka factor-κB (NF-κB), isbeddelka koritaanka factor-1 (TGF-1), iyo burooyinka necrosis factor-α (TNF-α)

ITM = ilo aan dabiici ahayn oo caadi ah oo macdanta raadadka ah (heerka ku darista 0.2% ee cuntooyinka)

CTM = 50:50 macdan methionine hydroxy analoog chelate iyo macdan aan dabiici ahayn (heerka ku darista 0.2% cuntooyinka)

3)Xoolaha

Lo'da caanaha naaska nuujinaysa, iyadoo badh ka mid ah copper sulfate lagu beddelayohydroxy methionine coppersi weyn ayay u kordhisay fiirsashada naxaasta balaasmaha, waxay hagaajisay dheefshiidka faybarka saabuunta dhexdhexaadka ah (NDF) iyo faybarka saabuunta aashitada (ADF), waxayna kordhisay wax soo saarka caanaha iyo 4% wax soo saarka caanaha lagu saxay dufanka. Natiijooyinkani waxay muujinayaan in qayb ahaan lagu beddelo naxaasta sulfate (HMTBA)₂-Cu cuntooyinka lo'da caanaha ay tahay istaraatiijiyad nafaqo oo waxtar leh.

Shaxda 3aad Saamaynta methionine hydroxy Cu [(HMTBA)2-Cu] ee ku saabsan halabuurka caanaha ee lo'da

Shay	S	SM	M	SEM	Qiimaha P
DMI, kg/d	19.2	20.3	19.8	0.35	0.23
Wax soo saarka caanaha, kg/d	28.8	33.8	31.3	1.06	0.08
Dufan, %	3.81	3.74	3.75	0.06	0.81
Borotiin, %	3.34	3.28	3.28	0.04	0.19
Laktoos, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Wax soo saarka dufanka, kg/d	1.04	1.22	1.10	0.04	0.09
Wax-soo-saarka borotiinka, kg/d	0.92	0.92	0.90	0.03	0.72
Wax-soo-saarka laktooska, kg/d	1.23	1.23	1.21	0.04	0.45
Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/d	26.1	30.1	27.5	0.91	0.06

Daawaynta: S = Cu sulfate oo keliya: 12 mg oo Cu ah oo ay bixiso CuSO4 halkii kiilo ee isku-darka; SM = Cu sulfate iyo (HMTBA)2-Cu: 6 mg oo Cu ah oo ay bixiso CuSO4, iyo 6 mg oo kale oo Cu ah oo ay bixiso (HMTBA)2-Cu halkii kiilo ee isku-darka; M = (HMTBA)2-Cu oo keliya: 12 mg oo Cu ah oo ay bixiso (HMTBA)2-Cu halkii kiilo ee isku-darka.